Time line

NAD discovered

Nobel prize awarded to Arthur Harden and William John Young for helping the world understand the fermentation process and discovering the structure of NAD

View More 1906

NAD Expanded

Otto Warburg, another Nobel laureate, discovered NAD serves as a relay for biological relay of electrons

View More 1930's

Human Supplementation

Conrad Elvehjem discovered that NAD+ supplementation cured pellagra, or “Black Tongue" which stems from a niacin deficiency and is now regularly treated with nicotinamide, one of the precursors to NMN.

View More 1937

Principles of Replication & Transcription

Arthur Kornberg’s research on NAD+ throughout the 40’s and 50’ was instrumental in leading him to discover the principles behind DNA replication and RNA transcription, two processes vital for life.

View More 1940's & 50's

Nicotinic Acid to NAD

Jack Preiss and Philip Handler discovered three biochemical steps, by which nicotinic acid is converted to NAD

View More 1958

Role in DNA Repair

Chambon, Weill, and Mandel reported that NMN provided the energy needed to activate an important nuclear enzyme leading to the discovery of PARP

View More 1963

Major Function in Mammals

Rechsteiner and his colleagues found evidence NAD+ seemed likely to have “some other major function” in mammalian cells. This lead to the discovery of sirtuins

View More 1978

Extends Lifespan

David Sinclair & team demonstrated that NMN can extend lifespan of mice.

View More 2014

Blockbuster Supplement

NMN has become a global phenomenon with sales over $200 million.

View More 2023

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NMN: From Discovery To You!

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